The synthesis and hydrolysis of dimethyl acetals catalyzed by sulfated metal oxides. An efficient method for protecting carbonyl groups

Chiu Hsun Lin, Shawn D. Lin, Yi Hung Yang, Tsung Po Lin

研究成果: Article同行評審

26 引文 斯高帕斯(Scopus)

摘要

Sulfated metal oxides including SO42-/ZrO2, SO42- /TiO2, SO42- /HfO2, SO42- /Fe2O3, SO42- /SnO2, and SO42- /Al2O3 were highly efficient catalysts for the reaction of aldehydes and ketones with trimethyl orthoformate producing dimethyl acetals under mild reaction conditions. At room temperature, dimethyl acetal yields of 83-100% were obtained for the five carbonyl compounds chosen. These mesoporous solid acids also effectively catalyzed the hydrolysis of dimethyl acetal to regenerate the original carbonyl compounds in aqueous acetone. They not only provided an effective method for synthesizing dimethyl acetals of larger molecular size but also acted as a versatile catalyst for protecting and deprotecting carbonyl groups during organic synthesis.

原文English
頁(從 - 到)121-125
頁數5
期刊Catalysis Letters
73
發行號2-4
DOIs
出版狀態Published - 2001 五月

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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