Fabrication of a dipole-assisted solid phase extraction microchip for trace metal analysis in water samples

Tsung Ting Shih, I. Hsiang Hsu, Ping Hung Chen, Shun Niang Chen, Sheng Hao Tseng, Ming Jay Deng, Yang Wei Lin, Yuh Chang Sun

研究成果: Article

摘要

This paper describes a fabrication protocol for a dipole-assisted solid phase extraction (SPE) microchip available for trace metal analysis in water samples. A brief overview of the evolution of chip-based SPE techniques is provided. This is followed by an introduction to specific polymeric materials and their role in SPE. To develop an innovative dipole-assisted SPE technique, a chlorine (Cl)-containing SPE functionality was implanted into a poly(methyl methacrylate) (PMMA) microchip. Herein, diverse analytical techniques including contact angle analysis, Raman spectroscopic analysis, and laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) analysis were employed to validate the utility of the implantation protocol of the C-Cl moieties on the PMMA. The analytical results of the X-ray absorption near-edge structure (XANES) analysis also demonstrated the feasibility of the Cl-containing PMMA used as an extraction medium by virtue of the dipole-ion interactions between the highly electronegative C-Cl moieties and the positively charged metal ions.

原文English
文章編號e53500
期刊Journal of Visualized Experiments
2016
發行號114
DOIs
出版狀態Published - 2016 八月 7

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Chemical Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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  • 引用此

    Shih, T. T., Hsu, I. H., Chen, P. H., Chen, S. N., Tseng, S. H., Deng, M. J., Lin, Y. W., & Sun, Y. C. (2016). Fabrication of a dipole-assisted solid phase extraction microchip for trace metal analysis in water samples. Journal of Visualized Experiments, 2016(114), [e53500]. https://doi.org/10.3791/53500