Creation of biomolecule arrays by electrostatic immobilization on electron-beam-irradiated polystyrene thin films

M. N. Wybourne, Mingdi Yan, John F.W. Keana, J. C. Wu

研究成果: Article

19 引文 斯高帕斯(Scopus)

摘要

Thin polystyrene films irradiated by an electron beam to create trapped charge are shown to immobilize the positively-charged protein, avidin-fluorescein. Using electron-beam lithography, fluorescent patterns with a minimum feature size of 0.5 μm were formed. The electrostatic nature of the immobilization was supported by the spatial and temporal features of the immobilization process. Additional evidence for an electrostatic mechanism was obtained from experiments to screen the trapped charge density with poly-L-lysine.

原文English
頁(從 - 到)302-305
頁數4
期刊Nanotechnology
7
發行號3
DOIs
出版狀態Published - 1996 九月 1

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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