In this chapter, we attempt to present the development and applications of metal nanoparticle-based colorimetric assays. The sensing strategies are based on analyte-induced nanoparticle (NP) aggregation and dispersion. We begin with the preparation, stabilization, and surface functionalization of Au and Ag NPs. A general introduction of the optical properties of Au and Ag NPs briefly follows. After providing a general background, we concentrate on their applications of sensing analytes, including DNA, proteins, and small solutes, through interparticle crosslinking and noncrosslinking aggregation events.
|主出版物標題||From Bioimaging to Biosensors|
|主出版物子標題||Noble Metal Nanoparticles in Biodetection|
|發行者||Pan Stanford Publishing Pte. Ltd.|
|出版狀態||Published - 2012 一月 1|
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
- Materials Science(all)