Abstract
Five new sulfur-containing polybromoindoles, 2-methylsulfinyl-3-methylthio- 4,5,6-tribromoindole (1), 3-methylsulfinyl-2,4,6-tribromoindole (2), 4,6-dibromo-2,3-di(methylsulfinyl)indole (3), 3,3′-bis(2′- methylsulfinyl-2-methylthio-4,6,4′,6′-tetrabromo)indole (4), and 3,3-bis(4,6-dibromo-2-methylsulfinyl)indole (5), as well as seven known sulfur-containing polybromoindoles, 3-methylthio-2,4,6-tribromoindole (6), 3-methylthio-2,4,5,6-tetrabromoindole (7), 4,6-dibromo-2,3-di(methylthio)indole (8), 2,3-di(methylthio)-4,5,6-tribromoindole (9), 4,6-dibromo-2-methylsulfinyl- 3-(methylthio)indole (10), 4,6-dibromo-2-(methylthio)indole (11), and 3,3-bis(4,6-dibromo-2-methylthio)indole (12), have been isolated from the Formosan red alga Laurencia brongniartii. The structures were elucidated by extensive spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
| Original language | English |
|---|---|
| Pages (from-to) | 815-817 |
| Number of pages | 3 |
| Journal | Journal of Natural Products |
| Volume | 68 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2005 May 1 |
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry