Abstract
Five new sulfur-containing polybromoindoles, 2-methylsulfinyl-3-methylthio- 4,5,6-tribromoindole (1), 3-methylsulfinyl-2,4,6-tribromoindole (2), 4,6-dibromo-2,3-di(methylsulfinyl)indole (3), 3,3′-bis(2′- methylsulfinyl-2-methylthio-4,6,4′,6′-tetrabromo)indole (4), and 3,3-bis(4,6-dibromo-2-methylsulfinyl)indole (5), as well as seven known sulfur-containing polybromoindoles, 3-methylthio-2,4,6-tribromoindole (6), 3-methylthio-2,4,5,6-tetrabromoindole (7), 4,6-dibromo-2,3-di(methylthio)indole (8), 2,3-di(methylthio)-4,5,6-tribromoindole (9), 4,6-dibromo-2-methylsulfinyl- 3-(methylthio)indole (10), 4,6-dibromo-2-(methylthio)indole (11), and 3,3-bis(4,6-dibromo-2-methylthio)indole (12), have been isolated from the Formosan red alga Laurencia brongniartii. The structures were elucidated by extensive spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
| Original language | English |
|---|---|
| Pages (from-to) | 815-817 |
| Number of pages | 3 |
| Journal | Journal of Natural Products |
| Volume | 68 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2005 May 1 |
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All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry
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Sulfur-containing polybromoindoles from the formosan red alga Laurencia brongniartii. / El-Gamal, Ali A.; Wang, Wei Lung; Duh, Chang Yih.
In: Journal of Natural Products, Vol. 68, No. 5, 01.05.2005, p. 815-817.Research output: Contribution to journal › Article
TY - JOUR
T1 - Sulfur-containing polybromoindoles from the formosan red alga Laurencia brongniartii
AU - El-Gamal, Ali A.
AU - Wang, Wei Lung
AU - Duh, Chang Yih
PY - 2005/5/1
Y1 - 2005/5/1
N2 - Five new sulfur-containing polybromoindoles, 2-methylsulfinyl-3-methylthio- 4,5,6-tribromoindole (1), 3-methylsulfinyl-2,4,6-tribromoindole (2), 4,6-dibromo-2,3-di(methylsulfinyl)indole (3), 3,3′-bis(2′- methylsulfinyl-2-methylthio-4,6,4′,6′-tetrabromo)indole (4), and 3,3-bis(4,6-dibromo-2-methylsulfinyl)indole (5), as well as seven known sulfur-containing polybromoindoles, 3-methylthio-2,4,6-tribromoindole (6), 3-methylthio-2,4,5,6-tetrabromoindole (7), 4,6-dibromo-2,3-di(methylthio)indole (8), 2,3-di(methylthio)-4,5,6-tribromoindole (9), 4,6-dibromo-2-methylsulfinyl- 3-(methylthio)indole (10), 4,6-dibromo-2-(methylthio)indole (11), and 3,3-bis(4,6-dibromo-2-methylthio)indole (12), have been isolated from the Formosan red alga Laurencia brongniartii. The structures were elucidated by extensive spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
AB - Five new sulfur-containing polybromoindoles, 2-methylsulfinyl-3-methylthio- 4,5,6-tribromoindole (1), 3-methylsulfinyl-2,4,6-tribromoindole (2), 4,6-dibromo-2,3-di(methylsulfinyl)indole (3), 3,3′-bis(2′- methylsulfinyl-2-methylthio-4,6,4′,6′-tetrabromo)indole (4), and 3,3-bis(4,6-dibromo-2-methylsulfinyl)indole (5), as well as seven known sulfur-containing polybromoindoles, 3-methylthio-2,4,6-tribromoindole (6), 3-methylthio-2,4,5,6-tetrabromoindole (7), 4,6-dibromo-2,3-di(methylthio)indole (8), 2,3-di(methylthio)-4,5,6-tribromoindole (9), 4,6-dibromo-2-methylsulfinyl- 3-(methylthio)indole (10), 4,6-dibromo-2-(methylthio)indole (11), and 3,3-bis(4,6-dibromo-2-methylthio)indole (12), have been isolated from the Formosan red alga Laurencia brongniartii. The structures were elucidated by extensive spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
UR - http://www.scopus.com/inward/record.url?scp=20444462044&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20444462044&partnerID=8YFLogxK
U2 - 10.1021/np058001y
DO - 10.1021/np058001y
M3 - Article
C2 - 15921441
AN - SCOPUS:20444462044
VL - 68
SP - 815
EP - 817
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0163-3864
IS - 5
ER -