Structural characteristics and antioxidative capability of the soluble polysaccharides present in dictyophora indusiata (Vent. Ex Pers.) fish phallaceae

Chiu Lan Hsieh, Yaw Bee Ker, Kuan Chou Chen, Chiung Chi Peng, Robert Y. Peng

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-Sn, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44% w/w, their molecular weight (MW) ranged within 8014656kDa. D3, having the smallest MW 801kDa, exhibited the most potent scavenging effect against the diphenyl-picrylhydrazyl, OH(), and O 2 radicals, yielding IC50 values 0.11, 1.02 and 0.64mgmL(1), respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MW and monosaccharide profiles.

Original languageEnglish
Article number396013
JournalEvidence-based Complementary and Alternative Medicine
Volume2011
DOIs
Publication statusPublished - 2011

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine

Fingerprint Dive into the research topics of 'Structural characteristics and antioxidative capability of the soluble polysaccharides present in dictyophora indusiata (Vent. Ex Pers.) fish phallaceae'. Together they form a unique fingerprint.

Cite this