Abstract
Several features of the yeast mitochondrial genome, including high mutation rate, dynamic genomic structure, small effective population size, and dispensability for cellular viability, make it a promising candidate for generating hybrid incompatibility and driving speciation. Cytonuclear incompatibility, a specific type of Dobzhansky-Muller genetic incompatibility caused by improper interactions between mitochondrial and nuclear genomes, has previously been observed in a variety of organisms, yet its role in speciation remains obscure. Recent studies in Saccharomyces yeast species provide a new insight, with experimental evidence that cytonuclear incompatibility and DNA sequence divergence are both causes of the reproductive isolation of different yeast species. Interestingly, these two mechanisms seem to be perfectly complementary to each other in terms of their effects and evolutionary trajectories. Direct molecular analyses of the incompatible genes in yeasts have started to shed light on the evolutionary forces driving speciation.
| Original language | English |
|---|---|
| Pages (from-to) | 401-411 |
| Number of pages | 11 |
| Journal | BioEssays |
| Volume | 32 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2010 May 1 |
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All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
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Speciation through cytonuclear incompatibility : Insights from yeast and implications for higher eukaryotes. / Chou, Jui-Yu; Leu, Jun Yi.
In: BioEssays, Vol. 32, No. 5, 01.05.2010, p. 401-411.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Speciation through cytonuclear incompatibility
T2 - Insights from yeast and implications for higher eukaryotes
AU - Chou, Jui-Yu
AU - Leu, Jun Yi
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Several features of the yeast mitochondrial genome, including high mutation rate, dynamic genomic structure, small effective population size, and dispensability for cellular viability, make it a promising candidate for generating hybrid incompatibility and driving speciation. Cytonuclear incompatibility, a specific type of Dobzhansky-Muller genetic incompatibility caused by improper interactions between mitochondrial and nuclear genomes, has previously been observed in a variety of organisms, yet its role in speciation remains obscure. Recent studies in Saccharomyces yeast species provide a new insight, with experimental evidence that cytonuclear incompatibility and DNA sequence divergence are both causes of the reproductive isolation of different yeast species. Interestingly, these two mechanisms seem to be perfectly complementary to each other in terms of their effects and evolutionary trajectories. Direct molecular analyses of the incompatible genes in yeasts have started to shed light on the evolutionary forces driving speciation.
AB - Several features of the yeast mitochondrial genome, including high mutation rate, dynamic genomic structure, small effective population size, and dispensability for cellular viability, make it a promising candidate for generating hybrid incompatibility and driving speciation. Cytonuclear incompatibility, a specific type of Dobzhansky-Muller genetic incompatibility caused by improper interactions between mitochondrial and nuclear genomes, has previously been observed in a variety of organisms, yet its role in speciation remains obscure. Recent studies in Saccharomyces yeast species provide a new insight, with experimental evidence that cytonuclear incompatibility and DNA sequence divergence are both causes of the reproductive isolation of different yeast species. Interestingly, these two mechanisms seem to be perfectly complementary to each other in terms of their effects and evolutionary trajectories. Direct molecular analyses of the incompatible genes in yeasts have started to shed light on the evolutionary forces driving speciation.
UR - http://www.scopus.com/inward/record.url?scp=77951726798&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951726798&partnerID=8YFLogxK
U2 - 10.1002/bies.200900162
DO - 10.1002/bies.200900162
M3 - Review article
C2 - 20414898
AN - SCOPUS:77951726798
VL - 32
SP - 401
EP - 411
JO - BioEssays
JF - BioEssays
SN - 0265-9247
IS - 5
ER -