Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles

Mei Huey Lin; Han Jun Liu; Wei Cheng Lin; Chung Kai Kuo; Tsung Hsun Chuang

doi:10.1039/c5ob01747e

Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles

Mei Huey Lin, Han Jun Liu, Wei Cheng Lin, Chung Kai Kuo, Tsung Hsun Chuang

Department of Chemistry

Research output: Contribution to journal › Article

13 Citations (Scopus)

Abstract

A procedure has been developed for the regioselective, high yielding synthesis of 2H-indazoles that involves direct alkylation of indazoles with various allyl and benzyl bromides, and α-bromocarbonyl compounds.

Original language	English
Pages (from-to)	11376-11381
Number of pages	6
Journal	Organic and Biomolecular Chemistry
Volume	13
Issue number	46
DOIs	https://doi.org/10.1039/c5ob01747e
Publication status	Published - 2015 Sep 29

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles",

abstract = "A procedure has been developed for the regioselective, high yielding synthesis of 2H-indazoles that involves direct alkylation of indazoles with various allyl and benzyl bromides, and α-bromocarbonyl compounds.",

author = "Lin, {Mei Huey} and Liu, {Han Jun} and Lin, {Wei Cheng} and Kuo, {Chung Kai} and Chuang, {Tsung Hsun}",

year = "2015",

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doi = "10.1039/c5ob01747e",

language = "English",

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publisher = "Royal Society of Chemistry",

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T1 - Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles

AU - Lin, Mei Huey

AU - Liu, Han Jun

AU - Lin, Wei Cheng

AU - Kuo, Chung Kai

AU - Chuang, Tsung Hsun

PY - 2015/9/29

Y1 - 2015/9/29

N2 - A procedure has been developed for the regioselective, high yielding synthesis of 2H-indazoles that involves direct alkylation of indazoles with various allyl and benzyl bromides, and α-bromocarbonyl compounds.

AB - A procedure has been developed for the regioselective, high yielding synthesis of 2H-indazoles that involves direct alkylation of indazoles with various allyl and benzyl bromides, and α-bromocarbonyl compounds.

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U2 - 10.1039/c5ob01747e

DO - 10.1039/c5ob01747e

M3 - Article

AN - SCOPUS:84947764754

VL - 13

SP - 11376

EP - 11381

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 46

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