Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles

Mei Huey Lin, Han Jun Liu, Wei Cheng Lin, Chung Kai Kuo, Tsung Hsun Chuang

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A procedure has been developed for the regioselective, high yielding synthesis of 2H-indazoles that involves direct alkylation of indazoles with various allyl and benzyl bromides, and α-bromocarbonyl compounds.

Original languageEnglish
Pages (from-to)11376-11381
Number of pages6
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number46
DOIs
Publication statusPublished - 2015 Sep 29

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Indazoles
alkylation
Alkylation
bromides
synthesis

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Lin, Mei Huey ; Liu, Han Jun ; Lin, Wei Cheng ; Kuo, Chung Kai ; Chuang, Tsung Hsun. / Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles. In: Organic and Biomolecular Chemistry. 2015 ; Vol. 13, No. 46. pp. 11376-11381.
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Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles. / Lin, Mei Huey; Liu, Han Jun; Lin, Wei Cheng; Kuo, Chung Kai; Chuang, Tsung Hsun.

In: Organic and Biomolecular Chemistry, Vol. 13, No. 46, 29.09.2015, p. 11376-11381.

Research output: Contribution to journalArticle

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AU - Lin, Mei Huey

AU - Liu, Han Jun

AU - Lin, Wei Cheng

AU - Kuo, Chung Kai

AU - Chuang, Tsung Hsun

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