Photoacoustic correlation technique for low-speed flow measurement

Sung Liang Chen, Tao Ling, Sheng Wen Huang, Hyoung Won Baac, Yu Chung Chang, L. Jay Guo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A photoacoustic correlation spectroscopy (PACS) technique was proposed for the first time. This technique is inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS), which is widely used in the characterization of the dynamics of fluorescent species. The fluorescence intensity is measured in FCS while the acoustic signals are detected in PACS. To proof of concept, we demonstrated the flow measurement of light-absorbing beads probed by a pulsed laser. A PACS system with temporal resolution of 0.8 sec was built. Polymer microring resonators were used to detect the photoacoustic signals, which were then signal processed and used to obtain the autocorrelation curves. Flow speeds ranging from 249 to 15.1 μm/s with corresponding flow time from 4.42 to 72.5 sec were measured. The capability of low-speed flow measurement can potentially be used for detecting blood flow in relatively deep capillaries in biological tissues. Moreover, similar to FCS, PACS may have many potential applications in studying the dynamics of photoacoustic beads.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2010
DOIs
Publication statusPublished - 2010
EventPhotons Plus Ultrasound: Imaging and Sensing 2010 - San Francisco, CA, United States
Duration: 2010 Jan 242010 Jan 26

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7564
ISSN (Print)1605-7422

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2010
CountryUnited States
CitySan Francisco, CA
Period10-01-2410-01-26

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Chen, S. L., Ling, T., Huang, S. W., Baac, H. W., Chang, Y. C., & Guo, L. J. (2010). Photoacoustic correlation technique for low-speed flow measurement. In Photons Plus Ultrasound: Imaging and Sensing 2010 [75642I] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7564). https://doi.org/10.1117/12.840123