Photoacoustic correlation technique for low-speed flow measurement

Sung Liang Chen; Tao Ling; Sheng Wen Huang; Hyoung Won Baac; Yu-Chung Chang; L. Jay Guo

doi:10.1117/12.840123

Photoacoustic correlation technique for low-speed flow measurement

Sung Liang Chen, Tao Ling, Sheng Wen Huang, Hyoung Won Baac, Yu-Chung Chang, L. Jay Guo

Department of Electrical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

A photoacoustic correlation spectroscopy (PACS) technique was proposed for the first time. This technique is inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS), which is widely used in the characterization of the dynamics of fluorescent species. The fluorescence intensity is measured in FCS while the acoustic signals are detected in PACS. To proof of concept, we demonstrated the flow measurement of light-absorbing beads probed by a pulsed laser. A PACS system with temporal resolution of 0.8 sec was built. Polymer microring resonators were used to detect the photoacoustic signals, which were then signal processed and used to obtain the autocorrelation curves. Flow speeds ranging from 249 to 15.1 μm/s with corresponding flow time from 4.42 to 72.5 sec were measured. The capability of low-speed flow measurement can potentially be used for detecting blood flow in relatively deep capillaries in biological tissues. Moreover, similar to FCS, PACS may have many potential applications in studying the dynamics of photoacoustic beads.

Original language	English
Title of host publication	Photons Plus Ultrasound
Subtitle of host publication	Imaging and Sensing 2010
Volume	7564
DOIs	https://doi.org/10.1117/12.840123
Publication status	Published - 2010 May 3
Event	Photons Plus Ultrasound: Imaging and Sensing 2010 - San Francisco, CA, United States Duration: 2010 Jan 24 → 2010 Jan 26

Other

Other	Photons Plus Ultrasound: Imaging and Sensing 2010
Country	United States
City	San Francisco, CA
Period	10-01-24 → 10-01-26

All Science Journal Classification (ASJC) codes

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

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Chen, S. L., Ling, T., Huang, S. W., Baac, H. W., Chang, Y-C., & Guo, L. J. (2010). Photoacoustic correlation technique for low-speed flow measurement. In Photons Plus Ultrasound: Imaging and Sensing 2010 (Vol. 7564). [75642I] https://doi.org/10.1117/12.840123

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title = "Photoacoustic correlation technique for low-speed flow measurement",

abstract = "A photoacoustic correlation spectroscopy (PACS) technique was proposed for the first time. This technique is inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS), which is widely used in the characterization of the dynamics of fluorescent species. The fluorescence intensity is measured in FCS while the acoustic signals are detected in PACS. To proof of concept, we demonstrated the flow measurement of light-absorbing beads probed by a pulsed laser. A PACS system with temporal resolution of 0.8 sec was built. Polymer microring resonators were used to detect the photoacoustic signals, which were then signal processed and used to obtain the autocorrelation curves. Flow speeds ranging from 249 to 15.1 μm/s with corresponding flow time from 4.42 to 72.5 sec were measured. The capability of low-speed flow measurement can potentially be used for detecting blood flow in relatively deep capillaries in biological tissues. Moreover, similar to FCS, PACS may have many potential applications in studying the dynamics of photoacoustic beads.",

author = "Chen, {Sung Liang} and Tao Ling and Huang, {Sheng Wen} and Baac, {Hyoung Won} and Yu-Chung Chang and Guo, {L. Jay}",

year = "2010",

month = may,

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doi = "10.1117/12.840123",

language = "English",

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AU - Chen, Sung Liang

AU - Ling, Tao

AU - Huang, Sheng Wen

AU - Baac, Hyoung Won

AU - Chang, Yu-Chung

AU - Guo, L. Jay

PY - 2010/5/3

Y1 - 2010/5/3

N2 - A photoacoustic correlation spectroscopy (PACS) technique was proposed for the first time. This technique is inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS), which is widely used in the characterization of the dynamics of fluorescent species. The fluorescence intensity is measured in FCS while the acoustic signals are detected in PACS. To proof of concept, we demonstrated the flow measurement of light-absorbing beads probed by a pulsed laser. A PACS system with temporal resolution of 0.8 sec was built. Polymer microring resonators were used to detect the photoacoustic signals, which were then signal processed and used to obtain the autocorrelation curves. Flow speeds ranging from 249 to 15.1 μm/s with corresponding flow time from 4.42 to 72.5 sec were measured. The capability of low-speed flow measurement can potentially be used for detecting blood flow in relatively deep capillaries in biological tissues. Moreover, similar to FCS, PACS may have many potential applications in studying the dynamics of photoacoustic beads.

AB - A photoacoustic correlation spectroscopy (PACS) technique was proposed for the first time. This technique is inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS), which is widely used in the characterization of the dynamics of fluorescent species. The fluorescence intensity is measured in FCS while the acoustic signals are detected in PACS. To proof of concept, we demonstrated the flow measurement of light-absorbing beads probed by a pulsed laser. A PACS system with temporal resolution of 0.8 sec was built. Polymer microring resonators were used to detect the photoacoustic signals, which were then signal processed and used to obtain the autocorrelation curves. Flow speeds ranging from 249 to 15.1 μm/s with corresponding flow time from 4.42 to 72.5 sec were measured. The capability of low-speed flow measurement can potentially be used for detecting blood flow in relatively deep capillaries in biological tissues. Moreover, similar to FCS, PACS may have many potential applications in studying the dynamics of photoacoustic beads.

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Y2 - 24 January 2010 through 26 January 2010

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