Abstract
An effective Pd(0) carbene complex was successfully employed in the decarboxylative coupling of the heteroaromatic carboxylic acids (imidazo[1,2-a]pyridine and isoxazole) with aryl halides. For carboxyindoles, either decarboxylative coupling or tandem C-H arylation and decarboxylation occurred, leading to the formation of C2-monoarylated indoles.
| Original language | English |
|---|---|
| Pages (from-to) | 9384-9390 |
| Number of pages | 7 |
| Journal | Journal of Organic Chemistry |
| Volume | 77 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - 2012 Oct 19 |
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All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Pd(0)-catalyzed decarboxylative coupling and tandem C-H arylation/decarboxylation for the synthesis of heteroaromatic biaryls. / Nandi, Debkumar; Jhou, Yang Ming; Lee, Jhen Yi; Kuo, Bing Chiuan; Liu, Chien Yu; Huang, Pei Wen; Lee, Hon Man.
In: Journal of Organic Chemistry, Vol. 77, No. 20, 19.10.2012, p. 9384-9390.Research output: Contribution to journal › Article
TY - JOUR
T1 - Pd(0)-catalyzed decarboxylative coupling and tandem C-H arylation/decarboxylation for the synthesis of heteroaromatic biaryls
AU - Nandi, Debkumar
AU - Jhou, Yang Ming
AU - Lee, Jhen Yi
AU - Kuo, Bing Chiuan
AU - Liu, Chien Yu
AU - Huang, Pei Wen
AU - Lee, Hon Man
PY - 2012/10/19
Y1 - 2012/10/19
N2 - An effective Pd(0) carbene complex was successfully employed in the decarboxylative coupling of the heteroaromatic carboxylic acids (imidazo[1,2-a]pyridine and isoxazole) with aryl halides. For carboxyindoles, either decarboxylative coupling or tandem C-H arylation and decarboxylation occurred, leading to the formation of C2-monoarylated indoles.
AB - An effective Pd(0) carbene complex was successfully employed in the decarboxylative coupling of the heteroaromatic carboxylic acids (imidazo[1,2-a]pyridine and isoxazole) with aryl halides. For carboxyindoles, either decarboxylative coupling or tandem C-H arylation and decarboxylation occurred, leading to the formation of C2-monoarylated indoles.
UR - http://www.scopus.com/inward/record.url?scp=84867733060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867733060&partnerID=8YFLogxK
U2 - 10.1021/jo3015837
DO - 10.1021/jo3015837
M3 - Article
C2 - 22998080
AN - SCOPUS:84867733060
VL - 77
SP - 9384
EP - 9390
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
SN - 0022-3263
IS - 20
ER -