Intermolecular hydrogen transfers in 2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene: A theoretical study

Mu Jeng Cheng, Ching-Han Hu

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The remarkable stability of N-heterocyclic carbenes has been an area of great interest in chemistry. However, prototype carbenes of these molecules, i.e. those with hydrogen atoms bearing on the nitrogens, have not been isolated as stable compounds. It is clear from our theoretical study that these prototype carbenes (2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene) should undergo intermolecular hydrogen transfers (forming imidazole and thiazole) easily at room temperature.

Original languageEnglish
Pages (from-to)3897-3899
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number23
DOIs
Publication statusPublished - 2001 Jun 4

Fingerprint

Hydrogen
Theoretical Models
Bearings (structural)
Thiazoles
Nitrogen
Atoms
Molecules
Temperature
carbene
imidazole

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

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Intermolecular hydrogen transfers in 2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene : A theoretical study. / Cheng, Mu Jeng; Hu, Ching-Han.

In: Tetrahedron Letters, Vol. 42, No. 23, 04.06.2001, p. 3897-3899.

Research output: Contribution to journalArticle

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