Abstract
The remarkable stability of N-heterocyclic carbenes has been an area of great interest in chemistry. However, prototype carbenes of these molecules, i.e. those with hydrogen atoms bearing on the nitrogens, have not been isolated as stable compounds. It is clear from our theoretical study that these prototype carbenes (2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene) should undergo intermolecular hydrogen transfers (forming imidazole and thiazole) easily at room temperature.
| Original language | English |
|---|---|
| Pages (from-to) | 3897-3899 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 42 |
| Issue number | 23 |
| DOIs | |
| Publication status | Published - 2001 Jun 4 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Intermolecular hydrogen transfers in 2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene : A theoretical study. / Cheng, Mu Jeng; Hu, Ching-Han.
In: Tetrahedron Letters, Vol. 42, No. 23, 04.06.2001, p. 3897-3899.Research output: Contribution to journal › Article
TY - JOUR
T1 - Intermolecular hydrogen transfers in 2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene
T2 - A theoretical study
AU - Cheng, Mu Jeng
AU - Hu, Ching-Han
PY - 2001/6/4
Y1 - 2001/6/4
N2 - The remarkable stability of N-heterocyclic carbenes has been an area of great interest in chemistry. However, prototype carbenes of these molecules, i.e. those with hydrogen atoms bearing on the nitrogens, have not been isolated as stable compounds. It is clear from our theoretical study that these prototype carbenes (2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene) should undergo intermolecular hydrogen transfers (forming imidazole and thiazole) easily at room temperature.
AB - The remarkable stability of N-heterocyclic carbenes has been an area of great interest in chemistry. However, prototype carbenes of these molecules, i.e. those with hydrogen atoms bearing on the nitrogens, have not been isolated as stable compounds. It is clear from our theoretical study that these prototype carbenes (2,3-dihydroimidazol-2-ylidene and 2,3-dihydrothiazol-2-ylidene) should undergo intermolecular hydrogen transfers (forming imidazole and thiazole) easily at room temperature.
UR - http://www.scopus.com/inward/record.url?scp=0035806337&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035806337&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(01)00605-0
DO - 10.1016/S0040-4039(01)00605-0
M3 - Article
AN - SCOPUS:0035806337
VL - 42
SP - 3897
EP - 3899
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 23
ER -