For last few decades, we have witnessed that the R&D workers have increasingly become more ambidextrous, that is, seeking both for efficiency and for innovation and growth. However, how High-tech industries strategically integrate both exploitation and exploration activities are still understudied. Based on the strategic management, idea search and generation, implementation and organizational design, the thesis develops a notion of innovation ambidexterity (IA) and elaborates IA into three dimensions: strategy, openness and innovativeness ambidexterity. An instrument of IA is developed to collect 52 R&D managers and 455 staffs. Regressions are deployed to test these hypotheses. The results support that the IA and consequences. The thesis confirms that IA plays a crucial role in strategically integrating, information searching and innovative activities. Some managerial implications to diagnose and to develop a integrate IA in high-technology industry are suggested.