Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans

Mei Huey Lin, Yu Chun Chen, Shih Hao Chiu, Yun Fan Chen, Tsung Hsun Chuang

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.

Original languageEnglish
Article number1713
JournalMolecules
Volume21
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1

Fingerprint

Furans
furans
Cyclization
Iodine
iodine
Rubiaceae
Dehydrogenation
synthesis
dehydrogenation
furan

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Lin, Mei Huey ; Chen, Yu Chun ; Chiu, Shih Hao ; Chen, Yun Fan ; Chuang, Tsung Hsun. / Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans. In: Molecules. 2016 ; Vol. 21, No. 12.
@article{7f81e2358083466bb1825688c077c556,
title = "Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans",
abstract = "A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.",
author = "Lin, {Mei Huey} and Chen, {Yu Chun} and Chiu, {Shih Hao} and Chen, {Yun Fan} and Chuang, {Tsung Hsun}",
year = "2016",
month = "12",
day = "1",
doi = "10.3390/molecules21121713",
language = "English",
volume = "21",
journal = "Molecules",
issn = "1420-3049",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "12",

}

Lin, MH, Chen, YC, Chiu, SH, Chen, YF & Chuang, TH 2016, 'Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans', Molecules, vol. 21, no. 12, 1713. https://doi.org/10.3390/molecules21121713

Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans. / Lin, Mei Huey; Chen, Yu Chun; Chiu, Shih Hao; Chen, Yun Fan; Chuang, Tsung Hsun.

In: Molecules, Vol. 21, No. 12, 1713, 01.12.2016.

Research output: Contribution to journal › Article

TY - JOUR

T1 - Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans

AU - Lin, Mei Huey

AU - Chen, Yu Chun

AU - Chiu, Shih Hao

AU - Chen, Yun Fan

AU - Chuang, Tsung Hsun

PY - 2016/12/1

Y1 - 2016/12/1

N2 - A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.

AB - A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.

UR - http://www.scopus.com/inward/record.url?scp=85007197644&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85007197644&partnerID=8YFLogxK

U2 - 10.3390/molecules21121713

DO - 10.3390/molecules21121713

M3 - Article

C2 - 28009840

AN - SCOPUS:85007197644

VL - 21

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 12

M1 - 1713

ER -

Lin MH, Chen YC, Chiu SH, Chen YF, Chuang TH. Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans. Molecules. 2016 Dec 1;21(12). 1713. https://doi.org/10.3390/molecules21121713

Access to Document