Hypervalent iodine(III)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans

Mei Huey Lin, Yu Chun Chen, Shih Hao Chiu, Yun Fan Chen, Tsung Hsun Chuang

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Abstract

A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.

Original languageEnglish
Article number1713
JournalMolecules
Volume21
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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