Gold nanosponges: Green synthesis, characterization, and cytotoxicity

Yang Wei Lin, Yi Cheng Chen, Chia Wei Wang, Wen Tsen Chen, Chao Ming Liu, Chung Yu Chen, Huan Tsung Chang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A simply approach for the synthesis of Au nanostructures in tea infusions at room temperature is developed. By controlling the concentrations of tea infusions, Au nanostructures in various shapes and sizes have been prepared. From 1× (original concentration) and 0.01×(100 times diluted) tea infusions, 52.2±8.1 nm Au nanosponges (T-Au NSs) and 23±2 nm spherical Au nanoparticles (T-Au NPs) were prepared. The phytochemicals present on the surface of T-Au NSs were proved by surface-assisted laser desorption/ionization mass spectrometry, Fourier transform infrared spectrometry and capillary electrophoresis coupled with UV detection. The energy-dispersive X-ray spectroscopy and powder X-ray diffraction data reveal pure crystalline structures of the T-Au NSs. The dark field scattering images observe that the T-Au NSs have significant affinity toward HeLa cells. The cytotoxicity of T-Au NSs on HeLa cells is through caspase-3 activation.

Original languageEnglish
Pages (from-to)6566-6574
Number of pages9
JournalJournal of Nanoscience and Nanotechnology
Volume13
Issue number10
DOIs
Publication statusPublished - 2013 Oct 1

Fingerprint

Tea
Cytotoxicity
Gold
gold
synthesis
electrophoresis
cells
spectroscopy
affinity
x rays
mass spectroscopy
Nanostructures
desorption
activation
HeLa Cells
ionization
nanoparticles
room temperature
scattering
diffraction

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics

Cite this

Lin, Y. W., Chen, Y. C., Wang, C. W., Chen, W. T., Liu, C. M., Chen, C. Y., & Chang, H. T. (2013). Gold nanosponges: Green synthesis, characterization, and cytotoxicity. Journal of Nanoscience and Nanotechnology, 13(10), 6566-6574. https://doi.org/10.1166/jnn.2013.7770
Lin, Yang Wei ; Chen, Yi Cheng ; Wang, Chia Wei ; Chen, Wen Tsen ; Liu, Chao Ming ; Chen, Chung Yu ; Chang, Huan Tsung. / Gold nanosponges : Green synthesis, characterization, and cytotoxicity. In: Journal of Nanoscience and Nanotechnology. 2013 ; Vol. 13, No. 10. pp. 6566-6574.
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Lin, YW, Chen, YC, Wang, CW, Chen, WT, Liu, CM, Chen, CY & Chang, HT 2013, 'Gold nanosponges: Green synthesis, characterization, and cytotoxicity', Journal of Nanoscience and Nanotechnology, vol. 13, no. 10, pp. 6566-6574. https://doi.org/10.1166/jnn.2013.7770

Gold nanosponges : Green synthesis, characterization, and cytotoxicity. / Lin, Yang Wei; Chen, Yi Cheng; Wang, Chia Wei; Chen, Wen Tsen; Liu, Chao Ming; Chen, Chung Yu; Chang, Huan Tsung.

In: Journal of Nanoscience and Nanotechnology, Vol. 13, No. 10, 01.10.2013, p. 6566-6574.

Research output: Contribution to journalArticle

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