Fabrication of a dipole-assisted solid phase extraction microchip for trace metal analysis in water samples

Tsung Ting Shih, I. Hsiang Hsu, Ping Hung Chen, Shun Niang Chen, Sheng Hao Tseng, Ming Jay Deng, Yang Wei Lin, Yuh Chang Sun

Research output: Contribution to journalArticle

Abstract

This paper describes a fabrication protocol for a dipole-assisted solid phase extraction (SPE) microchip available for trace metal analysis in water samples. A brief overview of the evolution of chip-based SPE techniques is provided. This is followed by an introduction to specific polymeric materials and their role in SPE. To develop an innovative dipole-assisted SPE technique, a chlorine (Cl)-containing SPE functionality was implanted into a poly(methyl methacrylate) (PMMA) microchip. Herein, diverse analytical techniques including contact angle analysis, Raman spectroscopic analysis, and laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) analysis were employed to validate the utility of the implantation protocol of the C-Cl moieties on the PMMA. The analytical results of the X-ray absorption near-edge structure (XANES) analysis also demonstrated the feasibility of the Cl-containing PMMA used as an extraction medium by virtue of the dipole-ion interactions between the highly electronegative C-Cl moieties and the positively charged metal ions.

Original languageEnglish
Article numbere53500
JournalJournal of Visualized Experiments
Volume2016
Issue number114
DOIs
Publication statusPublished - 2016 Aug 7

Fingerprint

Metal analysis
Solid Phase Extraction
Chlorine
Metals
Fabrication
Polymethyl Methacrylate
Water
Polymethyl methacrylates
Ions
Laser Therapy
Inductively coupled plasma mass spectrometry
Spectroscopic analysis
X ray absorption
Laser ablation
Mass Spectrometry
Contact angle
Metal ions
X-Rays
Trace metals
Polymers

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Chemical Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Shih, T. T., Hsu, I. H., Chen, P. H., Chen, S. N., Tseng, S. H., Deng, M. J., ... Sun, Y. C. (2016). Fabrication of a dipole-assisted solid phase extraction microchip for trace metal analysis in water samples. Journal of Visualized Experiments, 2016(114), [e53500]. https://doi.org/10.3791/53500
Shih, Tsung Ting ; Hsu, I. Hsiang ; Chen, Ping Hung ; Chen, Shun Niang ; Tseng, Sheng Hao ; Deng, Ming Jay ; Lin, Yang Wei ; Sun, Yuh Chang. / Fabrication of a dipole-assisted solid phase extraction microchip for trace metal analysis in water samples. In: Journal of Visualized Experiments. 2016 ; Vol. 2016, No. 114.
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Fabrication of a dipole-assisted solid phase extraction microchip for trace metal analysis in water samples. / Shih, Tsung Ting; Hsu, I. Hsiang; Chen, Ping Hung; Chen, Shun Niang; Tseng, Sheng Hao; Deng, Ming Jay; Lin, Yang Wei; Sun, Yuh Chang.

In: Journal of Visualized Experiments, Vol. 2016, No. 114, e53500, 07.08.2016.

Research output: Contribution to journalArticle

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