Exploring the Stability of Gold Nanoparticles by Experimenting with Adsorption Interactions of Nanomaterials in an Undergraduate Lab

Chi Feng Lee, Pei Yun You, Ying Chiao Lin, Tsai Ling Hsu, Pi Yun Cheng, Yu Xuan Wu, Chi Shun Tseng, Sheng Wen Chen, Huey Por Chang, Yang-Wei Lin

Research output: Contribution to journalArticle

15 Citations (Scopus)


The proposed experiment can help students to understand the factors involved in the stability of gold nanoparticles (Au NPs) by exploring the adsorption interaction between Au NPs and various substances. The students in this study found that the surface plasmon resonance band of Au NP solutions underwent a red shift (i.e., from 520 to 650 nm) because of NaCl-induced aggregation caused by the elimination of the repulsive electrostatic force. In addition, a sufficient amount of bovine serum albumin molecules (29.4 nM) adsorbed on the surface of Au NPs (1.8 nM) through electrostatic interactions provides steric barriers that hinder electrolyte-induced aggregation. This experiment was performed in the fall 2014 semester to improve the recognition of nanoscale science and engineering concepts of undergraduates. (Figure Presented).

Original languageEnglish
Pages (from-to)1066-1070
Number of pages5
JournalJournal of Chemical Education
Issue number6
Publication statusPublished - 2015 Jun 9


All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Education

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