Explore the functional connectivity between brain regions during a chemistry working memory task

Wen Chi Chou, Jeng Ren Duann, Hsiao Ching She, Li Yu Huang, Tzyy Ping Jung

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Previous studies have rarely examined how temporal dynamic patterns, event-related coherence, and phase-locking are related to each other. This study assessed reaction-time sorted spectral perturbation and event-related spectral perturbation in order to examine the temporal dynamic patterns in the frontal midline (F), central parietal (CP), and occipital (O) regions during a chemistry working memory task at theta, alpha, and beta frequencies. Furthermore, the functional connectivity between F-CP, CP-O, and F-O were assessed by component event-related coherence (ERCoh) and component phase-locking (PL) at different frequency bands. In addition, this study examined whether the temporal dynamic patterns are consistent with the functional connectivity patterns across different frequencies and time courses. Component ERCoh/PL measured the interactions between different independent components decomposed from the scalp EEG, mixtures of time courses of activities arising from different brain, and artifactual sources. The results indicate that the O and CP regions' temporal dynamic patterns are similar to each other. Furthermore, pronounced component ERCoh/PL patterns were found to exist between the O and CP regions across each stimulus and probe presentation, in both theta and alpha frequencies. The consistent theta component ERCoh/PL between the F and O regions was found at the first stimulus and after probe presentation. These findings demonstrate that temporal dynamic patterns at different regions are in accordance with the functional connectivity patterns. Such coordinated and robust EEG temporal dynamics and component ERCoh/PL patterns suggest that these brain regions' neurons work together both to induce similar event-related spectral perturbation and to synchronize or desynchronize simultaneously in order to swiftly accomplish a particular goal. The possible mechanisms for such distinct component phase-locking and coherence patterns were also further discussed.

Original languageEnglish
Article numbere0129019
JournalPLoS ONE
Volume10
Issue number6
DOIs
Publication statusPublished - 2015 Jun 3

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Short-Term Memory
Brain
chemistry
brain
Data storage equipment
Parietal Lobe
Electroencephalography
Occipital Lobe
Frequency bands
Neurons
neurons
Scalp
Reaction Time

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

Cite this

Chou, Wen Chi ; Duann, Jeng Ren ; She, Hsiao Ching ; Huang, Li Yu ; Jung, Tzyy Ping. / Explore the functional connectivity between brain regions during a chemistry working memory task. In: PLoS ONE. 2015 ; Vol. 10, No. 6.
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Explore the functional connectivity between brain regions during a chemistry working memory task. / Chou, Wen Chi; Duann, Jeng Ren; She, Hsiao Ching; Huang, Li Yu; Jung, Tzyy Ping.

In: PLoS ONE, Vol. 10, No. 6, e0129019, 03.06.2015.

Research output: Contribution to journalArticle

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