Evolution of long centromeres in fire ants

Yu Ching Huang, Chih Chi Lee, Chia Yi Kao, Ni Chen Chang, Chung-Chi Lin, Dewayne Shoemaker, John Wang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Centromeres are essential for accurate chromosome segregation, yet sequence conservation is low even among closely related species. Centromere drive predicts rapid turnover because some centromeric sequences may compete better than others during female meiosis. In addition to sequence composition, longer centromeres may have a transmission advantage. Results: We report the first observations of extremely long centromeres, covering on average 34 % of the chromosomes, in the red imported fire ant Solenopsis invicta. By comparison, cytological examination of Solenopsis geminata revealed typical small centromeric constrictions. Bioinformatics and molecular analyses identified CenSol, the major centromeric satellite DNA repeat. We found that CenSol sequences are very similar between the two species but the CenSol copy number in S. invicta is much greater than that in S. geminata. In addition, centromere expansion in S. invicta is not correlated with the duplication of CenH3. Comparative analyses revealed that several closely related fire ant species also possess long centromeres. Conclusions: Our results are consistent with a model of simple runaway centromere expansion due to centromere drive. We suggest expanded centromeres may be more prevalent in hymenopteran insects, which use haplodiploid sex determination, than previously considered.

Original languageEnglish
Article number189
JournalBMC Evolutionary Biology
Volume16
Issue number1
DOIs
Publication statusPublished - 2016 Sep 15

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fire ants
centromeres
ant
chromosome
Solenopsis invicta
sex determination
bioinformatics
Solenopsis geminata
turnover
insect
DNA
satellite DNA
chromosome segregation
meiosis
chromosomes
insects
gender

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics

Cite this

Huang, Y. C., Lee, C. C., Kao, C. Y., Chang, N. C., Lin, C-C., Shoemaker, D., & Wang, J. (2016). Evolution of long centromeres in fire ants. BMC Evolutionary Biology, 16(1), [189]. https://doi.org/10.1186/s12862-016-0760-7
Huang, Yu Ching ; Lee, Chih Chi ; Kao, Chia Yi ; Chang, Ni Chen ; Lin, Chung-Chi ; Shoemaker, Dewayne ; Wang, John. / Evolution of long centromeres in fire ants. In: BMC Evolutionary Biology. 2016 ; Vol. 16, No. 1.
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Huang, YC, Lee, CC, Kao, CY, Chang, NC, Lin, C-C, Shoemaker, D & Wang, J 2016, 'Evolution of long centromeres in fire ants', BMC Evolutionary Biology, vol. 16, no. 1, 189. https://doi.org/10.1186/s12862-016-0760-7

Evolution of long centromeres in fire ants. / Huang, Yu Ching; Lee, Chih Chi; Kao, Chia Yi; Chang, Ni Chen; Lin, Chung-Chi; Shoemaker, Dewayne; Wang, John.

In: BMC Evolutionary Biology, Vol. 16, No. 1, 189, 15.09.2016.

Research output: Contribution to journalArticle

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Huang YC, Lee CC, Kao CY, Chang NC, Lin C-C, Shoemaker D et al. Evolution of long centromeres in fire ants. BMC Evolutionary Biology. 2016 Sep 15;16(1). 189. https://doi.org/10.1186/s12862-016-0760-7