Efficient cross-coupling reactions of aryl chlorides and bromides with phenyl- or vinyltrimethoxysilane mediated by a palladium/imidazolium chloride system

Hon Man Lee, Steven P. Nolan

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diagram presented A combination of palladium acetate and the imidazolium salt IPr-HCI (1, IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) has proven to be highly efficient in the cross coupling reactions of aryl bromides and electron-deficient aryl chlorides with phenyltrimethoxysilane or vinyltrimethoxysilane. The catalytic performance of this system was found to be comparable to that of systems using PCy3 and P(o-tol)3.

Original languageEnglish
Pages (from-to)2053-2055
Number of pages3
JournalOrganic Letters
Issue number14
Publication statusPublished - 2000 Jul 13


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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