Over the past two decades, PBL approach has been widely adopted as a principal teaching approach and proved to be an effective technique to enhance learner performance as well as other academic related skills, such as critical thinking, problem solving and autonomy, but the studies on PBL has been mainly conducted in medical related fields. Literature review on PBL in other disciplines remains relatively scant. In view of this, this panel containing five separate but interrelated PBL empirical studies will go beyond the scope of the medical discipline. Considering PBL is a multi-dimensional concept, each of the study will deal with a distinct aspect/skill as a result of PBL practice. Chen's study examines self-regulated and shared-regulated learning in the PBL environment. Lin's study focuses on fostering student affections for English language learners. Wu's study deals with another vital PBL notion, based on the social constructivist theory, resulting in active interaction and cooperation among language learners in the learning process of PBL instruction. Wong will present a conceptual design that hybridizes seamless language learning and problem-based language learning. Finally, Yamamoto's contribution is to share with the audience Kansai University's collaborative pilot curriculum for PBL in global teams.