Design of bipolar pulse generator for biomedical applications

Liang Rui Chen, Neng Yi Chu, Min Hui Yang, Yan Ming Su

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Electric pulse field methods are powerful tools for cell characterization and manipulation and are wildly used in biotechnology and medical applications. A pulse generator (PG) is the device which provides the desired electric pulse field. In this paper, a low cost AC-Powered Bipolar PG (AC-BPG), directly powered by normal AC power (i.e., utility power), is proposed. Since there is no high-voltage DC power supply in the proposed AC-BPG, the circuit complexity and cost is effectively reduced. Furthermore, the voltage of the generated bipolar pulse of the AC-BPG can easily be controlled to match specific applications. This function is not easy to be implemented in conventional pulse generators after a fixed high-voltage DC power supply is selected. In order to assess the performance of the proposed AC-BPG, a prototype is designed, realized and tested. Experimental results show that the AC-BPG can actually generate a 0-1,300V pulse with 56 μs duration, without overshoot and ringing. Using a 1-4 mm standard commercial cuvette, the AC-BPG can provide electric pulse fields of 0-13 KV/cm to be used in bioelectronics, medical and industrial applications.

Original languageEnglish
Title of host publication2006 1st IEEE Conference on Industrial Electronics and Applications
DOIs
Publication statusPublished - 2006 Dec 1
Event2006 1st IEEE Conference on Industrial Electronics and Applications, ICIEA 2006 - Singapore, Singapore
Duration: 2006 May 242006 May 26

Publication series

Name2006 1st IEEE Conference on Industrial Electronics and Applications

Other

Other2006 1st IEEE Conference on Industrial Electronics and Applications, ICIEA 2006
CountrySingapore
CitySingapore
Period06-05-2406-05-26

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All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering
  • Industrial and Manufacturing Engineering

Cite this

Chen, L. R., Chu, N. Y., Yang, M. H., & Su, Y. M. (2006). Design of bipolar pulse generator for biomedical applications. In 2006 1st IEEE Conference on Industrial Electronics and Applications [4025906] (2006 1st IEEE Conference on Industrial Electronics and Applications). https://doi.org/10.1109/ICIEA.2006.257305