Convenient approaches to synthesis of furanoid sugar-aza-crown ethers from C-ribosyl azido aldehyde via a reductive amination/amidation

Yu Chi Hsieh, Jiun Ly Chir, Wei Zou, Hsiu Han Wu, An Tai Wu

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Abstract

A short and highly efficient route to the α-anomer of a furanoid sugar-aza-crown ether was developed by a one-pot reductive amination of an α-anomer C-ribosyl azido aldehyde. In addition, the β-anomer furanoid sugar-aza-crown ether was synthesized from a linear disaccharide precursor via amidation and then followed by microwave-assisted amide reduction.

Original languageEnglish
Pages (from-to)1020-1023
Number of pages4
JournalCarbohydrate Research
Volume344
Issue number8
DOIs
Publication statusPublished - 2009 May 26

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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