Antioxidant effects of dopamine and related compounds

Gow Chin Yen, Chiu Luan Hsieh

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

The antioxidant and free radical scavenging effects of dopamine, noradrenaline, tyramine, and tyrosine were investigated and compared with α-tocopherol. The antioxidant effect of dopamine and its related compounds on peroxidation of linoleic acid were in the order of dopamine > α-tocopherol = tyramine > tyrosine > noradrenaline as measured by the thiocyanate method. These amine compounds had reducing power, and a scavenging effect on reactive oxygen species, i.e., superoxide anion and hydroxyl radical. The results for reducing power and scavenging effect of these amine compounds had a similar trend as their inhibition of linoleic acid peroxidation. The antioxidant activity of these amine compounds in soybean oil was also evaluated by the Rancimat method. The induction time to reach l00meq/kg peroxide value (POV) of soybean oil for dopamine, α-tocopherol, tyramine, tyrosine, noradrenaline, and control were 9.0, 8.2, 8.0, 6.4, 4.6, and 4.3h, respectively. The antioxidant efficacy of amine compounds seems to be correlated with the numbers of hydroxy groups and their position on the phenolic ring.

Original languageEnglish
Pages (from-to)1646-1649
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume61
Issue number10
DOIs
Publication statusPublished - 1997 Jan

Fingerprint

Tyramine
Amines
Tocopherols
Dopamine
Scavenging
Antioxidants
Tyrosine
Norepinephrine
Soybean Oil
Linoleic Acid
Superoxides
Peroxides
Hydroxyl Radical
Free Radicals
Reactive Oxygen Species

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

@article{b93e8aee3833469088ac99cd32c96fd8,
title = "Antioxidant effects of dopamine and related compounds",
abstract = "The antioxidant and free radical scavenging effects of dopamine, noradrenaline, tyramine, and tyrosine were investigated and compared with α-tocopherol. The antioxidant effect of dopamine and its related compounds on peroxidation of linoleic acid were in the order of dopamine > α-tocopherol = tyramine > tyrosine > noradrenaline as measured by the thiocyanate method. These amine compounds had reducing power, and a scavenging effect on reactive oxygen species, i.e., superoxide anion and hydroxyl radical. The results for reducing power and scavenging effect of these amine compounds had a similar trend as their inhibition of linoleic acid peroxidation. The antioxidant activity of these amine compounds in soybean oil was also evaluated by the Rancimat method. The induction time to reach l00meq/kg peroxide value (POV) of soybean oil for dopamine, α-tocopherol, tyramine, tyrosine, noradrenaline, and control were 9.0, 8.2, 8.0, 6.4, 4.6, and 4.3h, respectively. The antioxidant efficacy of amine compounds seems to be correlated with the numbers of hydroxy groups and their position on the phenolic ring.",
author = "Yen, {Gow Chin} and Hsieh, {Chiu Luan}",
year = "1997",
month = "1",
doi = "10.1271/bbb.61.1646",
language = "English",
volume = "61",
pages = "1646--1649",
journal = "Bioscience, Biotechnology and Biochemistry",
issn = "0916-8451",
publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",
number = "10",

}

Antioxidant effects of dopamine and related compounds. / Yen, Gow Chin; Hsieh, Chiu Luan.

In: Bioscience, Biotechnology and Biochemistry, Vol. 61, No. 10, 01.1997, p. 1646-1649.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Antioxidant effects of dopamine and related compounds

AU - Yen, Gow Chin

AU - Hsieh, Chiu Luan

PY - 1997/1

Y1 - 1997/1

N2 - The antioxidant and free radical scavenging effects of dopamine, noradrenaline, tyramine, and tyrosine were investigated and compared with α-tocopherol. The antioxidant effect of dopamine and its related compounds on peroxidation of linoleic acid were in the order of dopamine > α-tocopherol = tyramine > tyrosine > noradrenaline as measured by the thiocyanate method. These amine compounds had reducing power, and a scavenging effect on reactive oxygen species, i.e., superoxide anion and hydroxyl radical. The results for reducing power and scavenging effect of these amine compounds had a similar trend as their inhibition of linoleic acid peroxidation. The antioxidant activity of these amine compounds in soybean oil was also evaluated by the Rancimat method. The induction time to reach l00meq/kg peroxide value (POV) of soybean oil for dopamine, α-tocopherol, tyramine, tyrosine, noradrenaline, and control were 9.0, 8.2, 8.0, 6.4, 4.6, and 4.3h, respectively. The antioxidant efficacy of amine compounds seems to be correlated with the numbers of hydroxy groups and their position on the phenolic ring.

AB - The antioxidant and free radical scavenging effects of dopamine, noradrenaline, tyramine, and tyrosine were investigated and compared with α-tocopherol. The antioxidant effect of dopamine and its related compounds on peroxidation of linoleic acid were in the order of dopamine > α-tocopherol = tyramine > tyrosine > noradrenaline as measured by the thiocyanate method. These amine compounds had reducing power, and a scavenging effect on reactive oxygen species, i.e., superoxide anion and hydroxyl radical. The results for reducing power and scavenging effect of these amine compounds had a similar trend as their inhibition of linoleic acid peroxidation. The antioxidant activity of these amine compounds in soybean oil was also evaluated by the Rancimat method. The induction time to reach l00meq/kg peroxide value (POV) of soybean oil for dopamine, α-tocopherol, tyramine, tyrosine, noradrenaline, and control were 9.0, 8.2, 8.0, 6.4, 4.6, and 4.3h, respectively. The antioxidant efficacy of amine compounds seems to be correlated with the numbers of hydroxy groups and their position on the phenolic ring.

UR - http://www.scopus.com/inward/record.url?scp=0031240589&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031240589&partnerID=8YFLogxK

U2 - 10.1271/bbb.61.1646

DO - 10.1271/bbb.61.1646

M3 - Article

C2 - 10336274

AN - SCOPUS:0031240589

VL - 61

SP - 1646

EP - 1649

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

SN - 0916-8451

IS - 10

ER -