A novel disposable electrochemical sensor packaging with application for the detection of uric acid

Zuo Xiang Gan, Han Sheng Chen, Yu Chang Lin, Kuan-Jung Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study is to develop a novel flip-chip on board packaging for an immersion electrochemical sensor which is able to detect the concentration of a target substance fast and accurately. The package was fabricated and the electrochemical measurement was performed to validate its function especially immersion capability and sensitivity. The calibration line for uric acid known concentrations were created firstly. Then test samples were measured and their values of concentration were determined according to the calibration line. Furthermore, the measurement results using the proposed electrochemical sensors were compared to the ones from the health examination in hospital where they use timed endpoint method typically. The comparison show that the measurement error between these two methods is less than 5% to represent the high consistency in the measurement of concentrations of uric acid. However, the new package with CV measurement provide the faster results of examination than the ones of hospital in regular process (24 hours). In summary, the proposed electrochemical sensor with flip-chip on board packaging technology demonstrate high accuracy of measurement, fast processing time, and low-cost for the application in uric acid detecting. More experiments are performed to offer a low-cost and fast detecting for a target substance in various applications.

Original languageEnglish
Title of host publication13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018
PublisherIEEE Computer Society
Pages165-168
Number of pages4
ISBN (Electronic)9781538656150
DOIs
Publication statusPublished - 2019 Jan 24
Event13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018 - Taipei, Taiwan
Duration: 2018 Oct 242018 Oct 26

Publication series

NameProceedings of Technical Papers - International Microsystems, Packaging, Assembly, and Circuits Technology Conference, IMPACT
Volume2018-October
ISSN (Print)2150-5934
ISSN (Electronic)2150-5942

Conference

Conference13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018
CountryTaiwan
CityTaipei
Period18-10-2418-10-26

Fingerprint

Electrochemical sensors
Packaging
Acids
Calibration
Measurement errors
Costs
Health
Processing
Experiments

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Cite this

Gan, Z. X., Chen, H. S., Lin, Y. C., & Chung, K-J. (2019). A novel disposable electrochemical sensor packaging with application for the detection of uric acid. In 13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018 (pp. 165-168). [8625822] (Proceedings of Technical Papers - International Microsystems, Packaging, Assembly, and Circuits Technology Conference, IMPACT; Vol. 2018-October). IEEE Computer Society. https://doi.org/10.1109/IMPACT.2018.8625822
Gan, Zuo Xiang ; Chen, Han Sheng ; Lin, Yu Chang ; Chung, Kuan-Jung. / A novel disposable electrochemical sensor packaging with application for the detection of uric acid. 13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018. IEEE Computer Society, 2019. pp. 165-168 (Proceedings of Technical Papers - International Microsystems, Packaging, Assembly, and Circuits Technology Conference, IMPACT).
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abstract = "This study is to develop a novel flip-chip on board packaging for an immersion electrochemical sensor which is able to detect the concentration of a target substance fast and accurately. The package was fabricated and the electrochemical measurement was performed to validate its function especially immersion capability and sensitivity. The calibration line for uric acid known concentrations were created firstly. Then test samples were measured and their values of concentration were determined according to the calibration line. Furthermore, the measurement results using the proposed electrochemical sensors were compared to the ones from the health examination in hospital where they use timed endpoint method typically. The comparison show that the measurement error between these two methods is less than 5{\%} to represent the high consistency in the measurement of concentrations of uric acid. However, the new package with CV measurement provide the faster results of examination than the ones of hospital in regular process (24 hours). In summary, the proposed electrochemical sensor with flip-chip on board packaging technology demonstrate high accuracy of measurement, fast processing time, and low-cost for the application in uric acid detecting. More experiments are performed to offer a low-cost and fast detecting for a target substance in various applications.",
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Gan, ZX, Chen, HS, Lin, YC & Chung, K-J 2019, A novel disposable electrochemical sensor packaging with application for the detection of uric acid. in 13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018., 8625822, Proceedings of Technical Papers - International Microsystems, Packaging, Assembly, and Circuits Technology Conference, IMPACT, vol. 2018-October, IEEE Computer Society, pp. 165-168, 13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018, Taipei, Taiwan, 18-10-24. https://doi.org/10.1109/IMPACT.2018.8625822

A novel disposable electrochemical sensor packaging with application for the detection of uric acid. / Gan, Zuo Xiang; Chen, Han Sheng; Lin, Yu Chang; Chung, Kuan-Jung.

13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018. IEEE Computer Society, 2019. p. 165-168 8625822 (Proceedings of Technical Papers - International Microsystems, Packaging, Assembly, and Circuits Technology Conference, IMPACT; Vol. 2018-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Gan ZX, Chen HS, Lin YC, Chung K-J. A novel disposable electrochemical sensor packaging with application for the detection of uric acid. In 13th International Microsystems, Packaging, Assembly and Circuits Technology Conference, IMPACT 2018. IEEE Computer Society. 2019. p. 165-168. 8625822. (Proceedings of Technical Papers - International Microsystems, Packaging, Assembly, and Circuits Technology Conference, IMPACT). https://doi.org/10.1109/IMPACT.2018.8625822