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• 2019

  Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells

  Chen, M. K., Peng, C. C., Maner, R. S., Zulkefli, N. D., Huang, S. M. & Hsieh, C. L., 2019 Jun 1, In : Life Sciences. 226, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  • geniposide
  • Fluoxetine
  • Neuronal Outgrowth
  • Neuroblastoma
  • Neurites
  3 Citations (Scopus)
• 2018

  Evaluation of the inhibitory effects of genipin on the fluoxetine-induced invasive and metastatic model in human HepG2 cells

  Tian, Y. S., Chen, K. C., Zulkefli, N. D., Maner, R. S. & Hsieh, C. L., 2018, In : Molecules. 3327.

  Research output: Contribution to journal › Article › peer-review

  • genipin
  • Fluoxetine
  • Hep G2 Cells
  • proteins
  • cancer
  5 Citations (Scopus)
• 2017

  Modifying the Sensory Properties of Cassava Starch via Simplified Pseudo-Single Step Oxidation-Esterification Process

  Ker, Y. B., Hsieh, C. L., Peng, C. C., Chen, J. C., Yen, X. Y., Chyau, C. C., Chen, K. C. & Peng, R. Y., 2017 Apr 1, In : Journal of Food Processing and Preservation. 41, 2, e12782.

  Research output: Contribution to journal › Article › peer-review

  • Manihot
  • Esterification
  • cassava starch
  • Starch
  • esterification
• 2016

  Novel Approach of Using Nutraceutic-Directed Caloric Antioxidant Density and Ion-Ratio for Evaluating Fruit's Health Quality

  Hsieh, C. L., Huang, S. M., Chen, L. I., Yu, C. M., Wong, C. H. & Peng, R. Y., 2016 Aug 1, In : Journal of Food Science. 81, 8, p. H2059-H2068

  Research output: Contribution to journal › Article › peer-review

  • Vitis
  • Mangifera
  • kiwifruit
  • Fruit
  • Pyrus
  1 Citation (Scopus)
• 2015

  Benign prostatic hyperplasia complicated with T1DM can be alleviated by treadmill exercise - evidences revealed by the rat model Voiding dysfunction

  Chen, K. C., Sung, S. Y., Lin, Y. T., Hsieh, C. L., Shen, K. H., Peng, C. C. & Peng, R. Y., 2015 Nov 17, In : BMC Urology. 15, 1, 113.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Hyperplasia
  • Type 1 Diabetes Mellitus
  • Androgen Receptors
  • Testosterone
  • Somatomedins
  4 Citations (Scopus)

• Cylophosphamide elicited intracranial hemorrhage via mitochondrial ROS-hif-1α-ATP depleting pathway - Preventive trials with folic acid, resveratrol and vitamin E

  Hsieh, C-L., Chen, K. C., Guan, W. W., Peng, C. C. & Peng, R. Y., 2015 Jan 1, In : RSC Advances. 5, 38, p. 30342-30353 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Resveratrol
  • Vitamins
  • Adenosinetriphosphate
  • Vitamin E
  • Folic Acid

• Gallic acid exhibits risks of inducing muscular hemorrhagic liposis and cerebral hemorrhage-its action mechanism and preventive strategy

  Hsieh, C. L., Lin, C. H., Wang, H. E., Peng, C. C. & Peng, R. Y., 2015 Feb, In : Phytotherapy Research. 29, 2, p. 267-280 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallic Acid
  • Cerebral Hemorrhage
  • Vitamin E
  • Acetylcysteine
  • Vascular Endothelial Growth Factor A
  2 Citations (Scopus)

• The teratogenicity and the action mechanism of gallic acid relating with brain and cervical muscles

  Hsieh, C. L., Lin, C. H., Chen, K. C., Peng, C. C. & Peng, R. Y., 2015 Jun 1, In : PLoS ONE. 10, 6, e0119516.

  Research output: Contribution to journal › Article › peer-review

  • Tea
  • Gallic Acid
  • teratogenicity
  • Peroxisome Proliferator-Activated Receptors
  • Liver
  3 Citations (Scopus)
• 2014

  Exercise rescued chronic kidney disease by attenuating cardiac hypertrophy through the cardiotrophin-1 → LIFR/gp 130 → JAK/STAT3 pathway

  Chen, K. C., Hsieh, C. L., Peng, C. C. & Peng, R. Y., 2014 Apr, In : European Journal of Preventive Cardiology. 21, 4, p. 507-520 14 p.

  Research output: Contribution to journal › Article › peer-review

  • cardiotrophin 1
  • OSM-LIF Receptors
  • Janus Kinases
  • Cardiomegaly
  • Chronic Renal Insufficiency
  9 Citations (Scopus)

• Resveratrol and vitamin E rescue valproic acid-induced teratogenicity: The mechanism of action

  Hsieh, C. L., Chen, K. C., Lin, P. X., Peng, C. C. & Peng, R. Y., 2014 Mar, In : Clinical and Experimental Pharmacology and Physiology. 41, 3, p. 210-219 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Resveratrol
  • Valproic Acid
  • Vitamin E
  • Embryonic Structures
  • Chickens
  13 Citations (Scopus)

• The proteomic and genomic teratogenicity elicited by valproic acid is preventable with resveratrol and α-tocopherol

  Chen, Y., Lin, P. X., Hsieh, C. L., Peng, C. C. & Peng, R. Y., 2014 Dec 31, In : PLoS ONE. 9, 12, 0116534.

  Research output: Contribution to journal › Article › peer-review

  • valproic acid
  • Proteomics
  • teratogenicity
  • Tocopherols
  • resveratrol
  7 Citations (Scopus)
• 2013

  Exercise ameliorates renal cell apoptosis in chronic kidney disease by intervening in the intrinsic and the extrinsic apoptotic pathways in a rat model

  Chen, K. C., Peng, C. C., Hsieh, C. L. & Peng, R. Y., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 368450.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Renal Insufficiency
  • Apoptosis
  • Doxorubicin
  • Kidney
  • Calpain
  19 Citations (Scopus)

• In vitro polyphenolics erythrocyte model and in vivo chicken embryo model revealed gallic acid to be a potential hemorrhage inducer: Physicochemical action mechanisms

  Ker, Y. B., Peng, C. C., Lin, C. H., Chen, K. C., Hsieh, C-L. & Peng, R. Y., 2013 Mar 18, In : Chemical Research in Toxicology. 26, 3, p. 325-335 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallic Acid
  • Chickens
  • Ions
  • Embryonic Structures
  • Hemolysis
  5 Citations (Scopus)

• Rutin (quercetin rutinoside) induced protein-energy malnutrition in chronic kidney disease, but quercetin acted beneficially

  Hsieh, C-L., Peng, C. C., Chen, K. C. & Peng, R. Y., 2013 Jul 31, In : Journal of Agricultural and Food Chemistry. 61, 30, p. 7258-7267 10 p.

  Research output: Contribution to journal › Article › peer-review

  • protein energy malnutrition
  • Rutin
  • Protein-Energy Malnutrition
  • kidney diseases
  • Quercetin
  14 Citations (Scopus)

• Unique bioactive polyphenolic profile of guava (Psidium guajava) budding leaf tea is related to plant biochemistry of budding leaves in early dawn

  Chang, C. H., Hsieh, C-L., Wang, H. E., Peng, C. C., Chyau, C. C. & Peng, R. Y., 2013 Mar 15, In : Journal of the Science of Food and Agriculture. 93, 4, p. 944-954 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Psidium
  • Psidium guajava
  • plant biochemistry
  • Tea
  • tea
  22 Citations (Scopus)

• Valproic acid substantially downregulated genes folr1, IGF2R, RGS2, COL6A3, EDNRB, KLF6, and pax-3, N-acetylcysteine alleviated most of the induced gene alterations in chicken embryo model

  Hsieh, C. L., Chen, K. C., Ding, C. Y., Tsai, W. J., Wu, J. F. & Peng, C. C., 2013, In : Romanian Journal of Morphology and Embryology. 54, 4, p. 993-1004 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin Receptors
  • Somatomedin Receptors
  • Acetylcysteine
  • Valproic Acid
  • Chickens
  10 Citations (Scopus)
• 2012

  Ferulic acid is nephrodamaging while gallic acid is renal protective in long term treatment of chronic kidney disease

  Peng, C. C., Hsieh, C. L., Wang, H. E., Chung, J. Y., Chen, K. C. & Peng, R. Y., 2012 Jun, In : Clinical Nutrition. 31, 3, p. 405-414 10 p.

  Research output: Contribution to journal › Article › peer-review

  • ferulic acid
  • Gallic Acid
  • Chronic Renal Insufficiency
  • Kidney
  • Matrix Metalloproteinases
  30 Citations (Scopus)

• Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, And N-acetylcysteine in chicken embryo model

  Hsieh, C. L., Wang, H. E., Tsai, W. J., Peng, C. C. & Peng, R. Y., 2012 Jan 27, In : Toxicology. 291, 1-3, p. 32-42 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetylcysteine
  • Valproic Acid
  • Ascorbic Acid
  • Folic Acid
  • Chickens
  25 Citations (Scopus)

• Selected nutraceutic screening by therapeutic effects on doxorubicin-induced chronic kidney disease

  Peng, C. C., Hsieh, C. L., Ker, Y. B., Wang, H. Y., Chen, K. C. & Peng, R. Y., 2012 Oct 1, In : Molecular Nutrition and Food Research. 56, 10, p. 1541-1558 18 p.

  Research output: Contribution to journal › Article › peer-review

  • kidney diseases
  • doxorubicin
  • Quercetin
  • quercetin
  • Chronic Renal Insufficiency
  11 Citations (Scopus)

• Swimming exercise prevents fibrogenesis in chronic kidney disease by inhibiting the myofibroblast transdifferentiation

  Peng, C. C., Chen, K. C., Hsieh, C. L. & Peng, R. Y., 2012 Jun 27, In : PLoS ONE. 7, 6, e37388.

  Research output: Contribution to journal › Article › peer-review

  • kidney diseases
  • Myofibroblasts
  • Swimming
  • exercise
  • Chronic Renal Insufficiency
  21 Citations (Scopus)

• Therapeutic discrepancy of diallyl trisulfide and diallyl disulfide in part may be attributed to the resonance-stabilization of allylic cations and trisulfide anions

  Hsieh, C. L., Chang, C. H., Wang, H. E., Chen, K. C., Chyau, C. C. & Peng, R. Y., 2012 Oct 1, In : Journal of Sulfur Chemistry. 33, 5, p. 527-539 13 p.

  Research output: Contribution to journal › Article › peer-review

  • diallyl trisulfide
  • diallyl disulfide
  • Anions
  • Cations
  • Stabilization
  2 Citations (Scopus)

• Valproic Acid Downregulates RBP4 and Elicits Hypervitaminosis A-Teratogenesis-A Kinetic Analysis on Retinol/Retinoic Acid Homeostatic System

  Chuang, C. M., Chang, C. H., Wang, H. E., Chen, K. C., Peng, C. C., Hsieh, C. L. & Peng, R. Y., 2012 Sep 19, In : PLoS ONE. 7, 9, e43692.

  Research output: Contribution to journal › Article › peer-review

  • hypervitaminosis A
  • Hypervitaminosis A
  • valproic acid
  • Teratogenesis
  • retinol-binding protein
  19 Citations (Scopus)
• 2011

  Contaminated process water and accumulated enthalpy in semi-product caused severe deterioration of ready-to-eat flour milo-flakes

  Peng, C. H., Lin, L. Y., Hsieh, C-L., Peng, C. C. & Peng, R. Y., 2011 Oct 1, In : Journal of Food Process Engineering. 34, 5, p. 1682-1694 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Flour
  • flakes
  • enthalpy
  • Sorghum bicolor
  • Enthalpy

• Structural characteristics and antioxidative capability of the soluble polysaccharides present in dictyophora indusiata (Vent. Ex Pers.) fish phallaceae

  Hsieh, C. L., Ker, Y. B., Chen, K. C., Peng, C. C. & Peng, R. Y., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 396013.

  Research output: Contribution to journal › Article › peer-review

  • Polysaccharides
  • Fishes
  • Monosaccharides
  • Molecular Weight
  • galactoglucan
  15 Citations (Scopus)

• The aqueous soluble polyphenolic fraction of Psidium guajava leaves exhibits potent anti-angiogenesis and anti-migration actions on DU145 cells

  Chen, K. C., Peng, C. C., Peng, C. H., Hsieh, C. L. & Peng, R. Y., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 219069.

  Research output: Contribution to journal › Article › peer-review

  • Psidium
  • Matrix Metalloproteinases
  • Tissue Inhibitor of Metalloproteinase-2
  • Interleukin-8
  • Vascular Endothelial Growth Factor A
  20 Citations (Scopus)