Abstract
A simple method has been developed for synthesis of γ-halo-enones. The approach employs a sequence involving initial indium-mediated allenylation reactions of phenacyl halides with propargyl bromide. This process is followed by acid-promoted rearrangement reactions of the formed homoallenic halohydrins. The new method can be incorporated into routes for the efficient synthesis of various five-membered heterocyclic compounds.
Original language | English |
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Pages (from-to) | 2751-2757 |
Number of pages | 7 |
Journal | Journal of Organic Chemistry |
Volume | 79 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2014 Mar 21 |
All Science Journal Classification (ASJC) codes
- Organic Chemistry